Our Mission For over 30 years, Thorne Research has been dedicated to enhancing the health and well-being of people worldwide by providing innovative, high-quality, research-based nutritional supplements, health diagnostics technology platforms, and the latest in medical education. Through our products and services, our passionate, talented staff, collaboration with a variety of innovative and expert strategic partners, and an unwavering commitment to integrity, Thorne Research strives to become a leading health-care company serving people around the world.
- Dietary Supplement
- Inositol Hexaniacinate - a Safer, Non-Flushing Alternative to Niacin
- Provides a Higher Amount of Niacin without the Flushing
- Unlike Time-Release Niacin - Niasafe is Easy on the Liver
- Supports Peripheral Vascular Circulation
- Supports Lipid Metabolism
Niacin has long been used to support good cardiovascular health. It has been proven effective at helping to maintain already normal levels of cholesterol.
The side effects of high amounts of niacin that may occur range from flushing and itching to liver toxicity and impaired glucose tolerance. Therefore, the need for a safer approach to niacin supplementation resulted in the investigation of niacin esters. One of the most widely studied niacin esters is inositol hexaniacinate (IHN). In numerous trials IHN has been found to be virtually free of the side effects associated with conventional niacin therapy. Pharmacokinetic studies show the IHN molecule is absorbed intact and slowly hydrolyzed in the bloodstream, releasing free niacin and inositol and having a diminished impact on the liver. Maximum serum levels are reached approximately 10 hours after ingestion, thus allowing for a more delayed release of niacin that reduces the risk of flushing.
A review of the literature reveals numerous positive studies on the use of IHN to support good circulatory health, particularly the support of vascular circulation to the extremities.
Suggested Use Take 1 capsule one to three times daily or as recommended by your health-care practitioner.